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Equate Extra Strength Anti-Itch and Skin Protectant Cream Diphenhydramine HCl 2%, 1 oz, Compare to Extra Strength Benadryl® Cream Active Ingredient

4.6 stars out of 2143 reviews
(4.6)|
2,143 ratings

Key item features

  • Active Ingredients: This product contains diphenhydramine hydrochloride 2 percent (topical analgesic) and zinc acetate 0.1 percent (skin protectant), which compares to the active ingredients of Extra Strength Benadryl Itch Stopping Cream
  • Fast Relief: Provides fast relief for most outdoor itches due to bug bites, sunburn and rashes from poison ivy, poison oak or poison sumac
  • Extra Strength Itch Relief: Equate Extra Strength Anti-Itch and Skin Protectant Cream also treats minor skin irritations, such as minor burns, scrapes and cuts
  • Rash Relief: Use Equate Extra Strength Anti-Itch and Skin Protectant Cream on poison ivy, poison oak and poison sumac for fast relief
  • FIRST AID: First aid anti-itch and skin protectant will help to keep you from itching irritated skin
Current price is $2.84$2.84/oz
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Columbus, 43215
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Customer ratings & reviews

4.6 out of 5 stars
stars2,143 ratings433 reviews
How item rating is calculated

Reviews summary

Pros
  • : Offers good value for the amount provided.
  • : Made with durable and sturdy components.
  • : Relieves skin irritations caused by insect bites.
  • : Relieves itch and calms bites quickly.
Neutral
  • : Can be pleasant and long-lasting, but also unpleasant and lingering.
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Showing 1-3 of 433 reviews

Apr 17, 2025
jill
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Calms My Itchy Skin, Fantastic ‘Equate Brand!!

nicely because any soap I use??? There's always a chance I'm going to itch! This does it what it says it does with a great price and no smell! skin rubbing against other skin! I'm very fair complected and this works nàcdxdddzfdzfdzfdfdzfddddddzxzddddzxdxzdxzdzxdddzfdzfddzfdzfdzfdfqicely because any soap I use there's always a chance I'm going to itch! It does it what it says it does with a great price and no smell! this cream does what it's supposed to do! It comes my skin from everything from soap irritation to just smaller bug bites! It's a fantastic price at the equate brand is marvelous! to just smaller bug bites! It's a fantastic price at the equate brand is marvelous!

Helpful?3HZLJPA4B35L228680027
Aug 24, 2025
Kathy
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

Product works quickly; roll-on makes it easy for me to apply to myself (and easy for others to help when necessary); treatment lasts several hours; I have used this product for a long time and never built-up a resistance to it.

Helpful?3HZLJPA4B35L228680027
Aug 12, 2025
Debbie
Top Reviewer
Item details
Multipack quantity: 1
5 out of 5 stars review

Verified Purchase

WOW! This works!

I have had post menopausal itch for years! I've literally tried everything to get relief and this cream worked instantly! The 2% hydrocortisone is amazing! Thank you, thank you! Finally some relief!

Helpful?3HZLJPA4B35L228680027